Overall, Wednesday is a good candidate for most important day of the week due to the inflation data and 10-year Treasury Note auction, but Friday could be pretty active also. The calmest day may be Thursday. However, stocks can be more unpredictable than bonds. With them having such a heavy influence on the bond and mortgage markets lately, any day may be active. Therefore, it would be extremely prudent to maintain contact with your mortgage professional if still floating an interest rate and closing in the near future.